Carcinoma prostate or cancer of the prostate is the type of cancer that develops into the prostate gland. At Aashray, we provide the latest procedures and treatments to treat cancer of the prostate and produce successful results.
The prostate is a small and walnut-shaped gland found in men that is located next to the bladder, that is, in the pelvis. It produces semen and prostatic fluid which nourishes and transports the sperm.
Carcinoma Prostate, also known as Prostate Cancer or Cancer of the Prostate, is a type of cancer that is developed in the prostate gland. However, it is important to understand that not all growths observed in the prostate are carcinogenic. The growths can be benign (not cancer) like BPH or malignant (cancer) that is prostate cancer.
During the initial stages of prostate cancer, often there are no symptoms but in some cases, cancer can cause symptoms that may feel similar to those of BPH or Prostate Enlargement.
However, one can always opt for screening to detect the symptoms or changes to indicate cancer as the levels of PSA in the blood are measured during the screening and high levels of the same may indicate the presence of cancer.
The symptoms of prostate cancer can be as follow:
Dr. Ashit Shah, the chief urologist at Aashray Urology Institute, has listed down risk factors for prostate cancer and they are as follow:
If cancer cells are found, the grade and risk of cancer will be determined.
The grade is a measure to decide the severity of the cancer cells and other factors dependent on it like their growth rate, spread etc.
Most commonly Gleason grading system is used to grade the tissues between 3 to 5 for prostate cancer.
Staging describes the location of cancer, its size, if it has started spreading etc. Prostate cancer is also measured in tumor stages. Staging the cancer is done by DRE and special imaging studies. These staging imaging tests are generally done for men with a Gleason grade of 7 or higher and a PSA higher than 10.
There is a range of options for prostate cancer and factors like grade & stage of cancer, risk level, age, health, treatment goals etc. play a major role while deciding the right treatment for you.
Both these options come with no side effects, complications, or risks that are associated with other treatment options such as surgery and therapies. However, these options do have the risk of the cancer growing or spreading during the follow-up visits which may make it harder to treat over time.
Surgical options are a good choice if cancer hasn’t spread beyond the prostate. In the case of radical prostatectomy, the main advantage is that the prostate with cancer is removed without any side effects and blood loss. Surgery also helps the doctor to understand your case better and plan further treatment if necessary.
Like any other major surgery, the risks of infection and bleeding may occur. Some people may experience complications right after the surgery whereas some people may encounter those later. For surgery, the side-effects may be as follow:
Please note that these risks and side effects are uncommon and will not occur in one patient. The utmost care and preventive measures are taken at Aashray Urology Institute to avoid the occurrence of risks and complications.
Radiation therapy is less invasive than surgery and be it external or internal, it is a good option for early-stage cancer. The main side effects of radiation therapy are as follow:
Cryotherapy or cryoablation involves controlled freezing of the prostate tissue. During cryotherapy, firstly, the prostate is imaged and measured and cryoprobes (special needles) are inserted into the prostate guided by the ultrasound for the freezing process. The freezing is done by using a very cold gas under anesthesia. The tissue is allowed to thaw and the procedure is repeated again and again until the cycles of freezing and thawing kill the cancer cells and some surrounding healthy tissue. This procedure is a good option for those who have small as well as advanced levels of prostate cancer and cannot receive surgery or radiation therapy due to health issues.
The types of focal therapy are as follow:
High-intensity focused ultrasound (HIFU) treatment involves heating the prostate with the help of ultrasound or high-energy sound waves to kill or destroy the cancer cells.
This procedure involves destroying the tumor by freezing it. It is done by using a needle-thin probe to circle the tumor with a special solution which then kills the cancer cells.
In this treatment, a “Nanoknife” is used to pass an electrical current through the tumor. The electricity creates very tiny openings (called pores) in the tumor's cells, leading to cell death.
Focal therapy is a good option for those who have a small tumor that has not spread beyond the prostate. The term focal therapy is used for different treatments that kill small tumors within the prostate without damaging nearby healthy tissue and the prostate.
Prostate cancer cells use the hormone testosterone to grow and hormone therapy treatment, also known as androgen deprivation therapy (ADT), stops the body from producing the same. Once the supply of testosterone is cut off, it is easier to kill or slow down the growth of cancer cells. Hormone therapy or ADT either with the help of drugs or surgically blocks or lowers the testosterone and starves prostate cancer cells. This therapy is used to treat advanced prostate cancer to shrink cancer and slow its growth.
In this type of ADT, certain medications known as luteinizing hormone-releasing hormone (LHRH) or gonadotropin-releasing hormone (GnRH) agonists and antagonists — prevent the body's cells from making testosterone. As a result, your testicles stop producing testosterone.
This surgery is performed to remove the testicles and glands that produce testosterone. Removal of testicles reduces testosterone levels in the body sharply. However, it is permanent and irreversible.
The following are the risks and side-effects associated with hormone therapy or ADT -
Please note that the mentioned risks are uncommon and will not occur on one patient. The utmost care and preventive measures are taken at Aashray Urology Institute to avoid the occurrence of any risks and complications.
This is a treatment for advanced-stage cancer. It is used to treat cancer that has spread to the other parts of the body. Chemotherapy is a cancer treatment that uses drugs to kill the rapidly growing other non-carcinogenic as well as cancer cells. Chemotherapy can be administered through a vein in your arm, in pill form, or both. This way drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy).
Dose to reduce the side effects this may cause. Often, chemotherapy is used with other treatments. It is not the main treatment for prostate cancer patients.
To reduce the side effects of chemotherapy, dose and frequency are carefully controlled. The side effects of this treatment depend on the drug, the dose, and how long the treatment lasts. The most common side effects are as follow:
This is a type of biological therapy. In immunotherapy, the immunity system of one’s body is used to fight cancer. The cancer cells produce proteins that help them hide from immune system cells; hence, the immune system does/may not attack cancer cells. This therapy interferes with this process as substances made by the body or in the laboratory are used to boost, direct, or restore the body’s natural defenses against cancer.
Prostate cancer immunotherapy can involve:
In this type immune cells produced by the body are taken to the laboratory and are engineered to fight prostate cancer and injected back into the body. It's an option for treating advanced prostate cancer that no longer responds to hormone therapy.
During this type of treatment, drugs are prescribed that help the immune system identify cancer cells and attack them. This is also an option for treating advanced prostate cancers that no longer respond to hormone therapy.
Dr. Ashit Shah is a senior consultant Urologist heading Aashray Urology Institute. After completing his M.B.B.S. and M.S. in General Surgery, he was awarded Diplomate of National Board (D.N.B.) in Genito-Urinary Surgery by the National Board of Examinations, New Delhi. He earned his Diplomate in Laparoscopic Urology from Louis Pasteur University, Strasbourg, France in the year 2006. Dr. Shah has a special interest in Endo-Urology, especially Urolithiasis i.e. Urinary Stone Disease. Having spent more than 27 years in the profession of Urology, he has experience of over 75,000 urological consultations and more than 15,000 surgeries. Being counted amongst the torch bearers of ethical and transparent medical practice in the city of Vadodara, he was conferred ‘Inspiring Urologist Award’ for the year 2019 by The Economic Times.